Detalhe da pesquisa
1.
Contrasting somatic mutation patterns in aging human neurons and oligodendrocytes.
Cell
; 187(8): 1955-1970.e23, 2024 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38503282
2.
Somatic cancer driver mutations are enriched and associated with inflammatory states in Alzheimer's disease microglia.
bioRxiv
; 2024 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38260600
3.
Contrasting patterns of somatic mutations in neurons and glia reveal differential predisposition to disease in the aging human brain.
bioRxiv
; 2023 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36711756
4.
Cell lineage analysis with somatic mutations reveals late divergence of neuronal cell types and cortical areas in human cerebral cortex.
bioRxiv
; 2023 Nov 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37986891
5.
Rates and Patterns of Clonal Oncogenic Mutations in the Normal Human Brain.
Cancer Discov
; 12(1): 172-185, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34389641
6.
Single-cell genome sequencing of human neurons identifies somatic point mutation and indel enrichment in regulatory elements.
Nat Genet
; 54(10): 1564-1571, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36163278
7.
Landmarks of human embryonic development inscribed in somatic mutations.
Science
; 371(6535): 1249-1253, 2021 03 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33737485
8.
MIPP-Seq: ultra-sensitive rapid detection and validation of low-frequency mosaic mutations.
BMC Med Genomics
; 14(1): 47, 2021 02 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33579278
9.
Comprehensive identification of somatic nucleotide variants in human brain tissue.
Genome Biol
; 22(1): 92, 2021 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33781308
10.
A novel specific PERK activator reduces toxicity and extends survival in Huntington's disease models.
Sci Rep
; 10(1): 6875, 2020 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32327686
11.
Implantation of 3D Constructs Embedded with Oral Mucosa-Derived Cells Induces Functional Recovery in Rats with Complete Spinal Cord Transection.
Front Neurosci
; 11: 589, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29163001
12.
Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network.
Science
; 356(6336)2017 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28450582
13.
Mesenchymal Stem Cell Transplantation Promotes Neurogenesis and Ameliorates Autism Related Behaviors in BTBR Mice.
Autism Res
; 9(1): 17-32, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26257137
14.
Harnessing neurogenesis for the possible treatment of Parkinson's disease.
J Comp Neurol
; 522(12): 2817-30, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24723264
15.
Astrocyte-like cells derived from human oral mucosa stem cells provide neuroprotection in vitro and in vivo.
Stem Cells Transl Med
; 3(3): 375-86, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24477074
16.
Dopaminergic-like neurons derived from oral mucosa stem cells by developmental cues improve symptoms in the hemi-parkinsonian rat model.
PLoS One
; 9(6): e100445, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24945922
17.
Mesenchymal stem cells protect from sub-chronic phencyclidine insult in vivo and counteract changes in astrocyte gene expression in vitro.
Eur Neuropsychopharmacol
; 23(9): 1115-23, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23116946
18.
Cell replacement therapy for Parkinson's disease: how close are we to the clinic?
Expert Rev Neurother
; 11(9): 1325-39, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21864078
19.
Nanoparticulate architecture of protein-based artificial viruses is supported by protein-DNA interactions.
Nanomedicine (Lond)
; 6(6): 1047-61, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21651444